【題目】— What's the matter _____your younger sister?
— She has a cough.
A.for
B.at
C.with
D.On

【答案】C
【解析】句意：--你的妹妹怎么了？--她患了重感冒。What's the matter with sb?……怎么了？用介詞with，根據(jù)題意。故選C。

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